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Metformin

Metformin: Metformin is a diabetes medication that can cause modest weight loss in some patients. It works by decreasing the absorption of glucose and reducing insulin resistance. Side effects include gastrointestinal symptoms such as diarrhea, abdominal pain, and bloating.

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Era of Discovery

1950s

Mechanism of Action

Decreases absorption of glucose and reduces insulin resistance

History of Use in the United States

Used as a diabetes medication, sometimes causes weight loss

Benefit of Weight Loss Agent or Medication

Modest weight loss in some patients

Possible Side Effects

Gastrointestinal symptoms, such as diarrhea, abdominal pain, and bloating

Current Regulatory Status in US

Available by prescription

See our discussion of metformin elsewhere:

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