Orlistat is currently (2012) the only FDA approved over-the-counter weight loss drug. It is totally unique in that it works by blocking fat absorption from the gut. It really works but at a cost that many people are unwilling to bear. The dietary fat this blocked by orlistat (when it is taken with a meal) often leads to extremely unpleasant gastrointestinal side effects like diarrhea and flatulence.

Brand names of orlistat are Alli and Xenical (the prescription version of Alli).

We don't stock Orlistat since it is available over the counter.